Challenging Depression: The Go-To Guide for Clinicians and by Mark Zetin, Cara T. Hoepner, Jennifer Kurth

By Mark Zetin, Cara T. Hoepner, Jennifer Kurth

Zetin, Hoepner, and Kurth clarify the factors of melancholy, how you can realize and diagnose different iterations of
depression, and the wide range of psychotherapeutic and psychopharmacological treatments on hand. Even
more very important, they convey sufferers how one can top paintings with their clinicians and clinicians the best way to most sensible support their patients.
The ebook is liberally sprinkled with case discussions, which demystify the remedy protocols and exhibit many of the ways
that consumers reply to remedy. during this e-book, doctors have a go-to table reference for his or her questions
about melancholy, and shoppers have a pleasant, obtainable creation to an differently intimidating ailment.

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Extra resources for Challenging Depression: The Go-To Guide for Clinicians and Patients

Sample text

Hepatology 31:984–989, 2000. C-C Chen, R-B Lu, Y-C Chen, M-F Wang, Y-C Chang, T-K Li, S-J Yin. Interaction between the functional polymorphisms of the alcohol-metabolism genes in protection against alcoholism. Am J Hum Genet 65:795–807, 1999. M Osier, AJ Pakstis, JR Kidd, J-F Lee, S-J Yin, H-C Ko, HJ Edenberg, R-B Lu, KK Kidd. Linkage disequilibrium at the ADH2 and ADH3 loci and risk of alcoholism. Am J Hum Genet 63:1147–1157, 1999. K Edman, W Maret. Alcohol dehydrogenase genes: restriction fragment length 24 72.

Hepatology 23:234–239, 1996. M Matsumoto, H Takahashi, K Maruyama, S Higuchi, S Matsushita, T Muramatsu, K Okuyama, A Yokoyama, M Nakano, H Ishii. Genotypes of alcohol-metabolizing enzymes and the risk for alcoholic chronic pancreatitis in Japanese alcoholics. Alcohol Clin Exp Res 20:289A–292A, 1996. Y-C Chao, T-H Young, H-S Tang, C-T Hsu. Alcoholism and alcoholic organ damage and genetic polymorphisms of alcohol metabolizing enzymes in Chinese patients. Hepatology 25:112–117, 1997. Y Maezawa, M Yamauchi, Y Searashi, K Takeda, Y Mizuhara, T Kimura, G Toda, H Suzuki, S Sakurai.

These association studies illustrate some of the difficulties that must be overcome. Although large-scale studies with linkage techniques and microsatellite markers have yielded QTLs in rats and mice, this has not yet been a route to discovery of alcohol sensitivity genes in humans. Investigation of the serotonin transporter gene (5-HTTLPR) appears to have arisen from the probable involve- 42 Whitfield ment of serotonin systems in impulsive or violent behavior, and from the existence of a deletion/insertion variant that affects gene transcription and transporter expression.

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