Bioinformatics: A Practical Guide to the Analysis of Genes by Andreas D. Baxevanis, B. F. Francis Ouellette

By Andreas D. Baxevanis, B. F. Francis Ouellette

Delivering biologists with the trendy instruments to unravel sensible difficulties in series facts research and administration, this revised and up to date variation deals a evaluate of the elemental ideas, in addition to discussions and comparisons of the to be had databases.

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Users will still be able to retrieve a record based on the accession number alone, without having to specify a particular version. In that case, the latest version of the record will be obtained by default, which is the current behavior for queries using Entrez and other retrieval programs. , aligning all alcohol dehydrogenase sequences from a particular taxonomic group) and wish to have their conclusions remain valid over time will want to reference sequences by accession and the given version number.

Rankin, B. (1996). Dr. Bob’s Painless Guide to the Internet and Amazing Things You Can Do With E-mail (San Francisco: No Starch Press). 2 THE NCBI DATA MODEL James M. Ostell National Center for Biotechnology Information National Library of Medicine National Institutes of Health Bethesda, Maryland Sarah J. Wheelan Department of Molecular Biology and Genetics The Johns Hopkins School of Medicine Baltimore, Maryland Jonathan A. Kans National Center for Biotechnology Information National Library of Medicine National Institutes of Health Bethesda, Maryland INTRODUCTION Why Use a Data Model?

Obviously, this complicated arrangement can result in problems when LOCUS names include numbers that inadvertently interfere with such series. In addition, there is no one sequence record that describes the whole assembled series, and there is no way to describe the distance between the individual pieces. There is no segmenting convention in the EMBL sequence database at all, so records derived from that source or distributed in that format lack even this imperfect information. ’’ Rather than containing the letters A, G, C, and T, the segmented sequence contains instructions on how it can be built from other sequences.

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