Application of Brain Oscillations in Neuropsychiatric by E. Başar, C. Başar-Eroĝlu, A. Özerdem, P.M. Rossini and G.G.

By E. Başar, C. Başar-Eroĝlu, A. Özerdem, P.M. Rossini and G.G. Yener (Eds.)

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Extra info for Application of Brain Oscillations in Neuropsychiatric Diseases: Selected Papers from “Brain Oscillations in Cognitive Impairment and Neurotransmitters” Conference, Istanbul, Turkey, 29 April–1 May 2011

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Hogan et al. (2003), Zheng-yan (2005), Yener et al. (2007, 2008, 2009), Gu¨ntekin et al. (2008), Dauwels et al. (2009), and Bas¸ar et al. (2010) published results on evoked/event-related coherence in AD patients. ” In the EEG analysis, only sporadically occurring coherences from hidden sources can be measured. Sensory evoked coherences reflect the property of sensory networks activated by a sensory stimulation. Event-related (or cognitive) coherences manifest coherent activity of sensory and cognitive networks triggered by a cognitive task.

2008) reported that, in first-episode patients, gamma phase synchrony was generally increased during auditory oddball task processing, especially over left centrotemporal sites in the 800 ms post-stimulus time window. Further research is needed to make robust conclusions on gamma response in auditory oddball paradigm in schizophrenia. 8. Analysis of drug/neurotransmitter application The following two examples show how drug applications significantly influence event-related (and/or evoked) brain oscillations.

Steady-state responses, which do not encompass a cognitive paradigm, elicit decreased gamma responses, whereas oddball paradigm evokes greatly variable gamma responses. Cognitive tasks with progressively increasing difficulty open the way to interpreting various brain functions or insights into differentiated cognitive deficits, as shown in Fig. 15. (a) The superposition of decreased delta activity and enhanced gamma activity in schizophrenic patients indicates the necessity of analyzing multiple oscillations in tasks with progressive increase of difficulty.

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