Allergens and allergen immunotherapy by Richard F. Lockey, Dennis K. Ledford

By Richard F. Lockey, Dennis K. Ledford

This paintings provides present details on allergens and the best tools and reason for immunotherapy remedy. It covers sufferer choice standards, allergen vaccine management, and monetary issues. This variation is revised and multiplied, containing 20 new chapters on parts together with immunobiology, tree pollens, mite allergens, blending allergen vaccines, debatable immunotherapy, aeobiology, allergen nomenclature, grass pollens, weed pollens, and cockroach allergens.

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Allergens and Allergen Immunotherapy: Second Edition, Revised and Expanded, edited by Richard F. Lockey and Samuel C. Bukantz ADDITIONAL VOLUMES IN PREPARATION Emergency Asthma, edited by Barry Brenner Food Hypersensitivity and Adverse Reactions, edited by Marianne Frieri and Brett Kettelhut Page i Allergens and Allergen Immunotherapy Second Edition, Revised and Expanded Edited By Richard F. Lockey Samuel C. Bukantz University of South Florida College of Medicine and James A. Haley Veterans Hospital Tampa, Florida MARCEL DEKKER, INC.

2) The pollen must be anemophilous or wind borne, as regards its mode of pollination. (3) The pollen must be produced in sufficiently large quantities. It is characteristic of wind-pollinated flowers in general that they produce pollen in far greater quantities than do flowers which are insect-pollinated. (4) The pollen must be sufficiently buoyant to be carried considerable distances. (5) The plant producing the pollen must be widely and abundantly distributed. Principles of preseasonal pollen desensitization were then applied to treatment of patients troubled the year round with vaccines of a variety of perennial allergens that had given positive skin reactions.

S. standard labeled in BAU. 2. AU: Allergy Unit. Before BAUs were assigned based on the ID50EAL method in the 1990s, standards were assigned potency units based on either major allergen content or arbitrary AUs in the 1980s. 100,000 AUs were assigned to FDA standards or company in-house standards based on in vitro tests analogous to WHO standards which are assigned arbitrary 100,000 International Units (IU) based on in vitro tests. 9 Fel d 1 U/mL were assigned arbitrary 100,000 AU/mL. Subsequently, these standardized cat vaccines were found to warrant 10,000 BAU/mL based on the ID50EAL method; therefore, the 100,000 AUs were changed to 10,000 BAUs for cat in the early 1990s (see Ref.

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